The awesome lysosome

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The awesome lysosome.

In the early 50s, Christian De Duve identified a new cellular structure, the lysosome, defined as the cell’s “suicide bag” (de Duve, 2005). Sixty years later, it is clear that the lysosome greatly exceeded the expectations of its discoverer. Over 50 different types of lysosomal storage diseases have been identified, each due to the deficiency or malfunction of a specific lysosomal protein. In a...

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ژورنال

عنوان ژورنال: EMBO Molecular Medicine

سال: 2016

ISSN: 1757-4676,1757-4684

DOI: 10.15252/emmm.201505966